Sahih Bukhari

Hadith #325

Narrated `Aisha:Fatima bint Abi Hubaish asked the Prophet, ""I got persistent bleeding (in between the periods) and do not become clean. Shall I give up prayers?"" He replied, ""No, this is from a blood vessel. Give up the prayers only for the days on which you usually get the menses and then take a bath and offer your prayers